1. Check ALL cord connections.
The cash drawer gets its power from the printer. Is the printer securely plugged into the “24V_USB” slot on the underside of the touch screen? Are the 2 cords leading from the this slot to the back of the printer securely in place? Is the printer on and is its light green? Does the printer have paper?
Is the cash drawer securely plugged into the back/bottom of the printer?
2.After checking and re-securing all these connections, log out and exit out of the Bb Register program until you can see the Microsoft Windows desktop. Then restart the Bb Register program and login. Doing this may get the NCR to recognize that the printer and cash drawer are now plugged in and resolve the issue.
3.Test the NO SALE button to see if the drawer opens. If there is still a problem, use the SUP (supervisor) key to make sure the lock is turned to an open position, not locked completely.
Add: Building B, No.58-70 Jinhui Road,Houxi Town, District of Jimei, Xiamen, Fujian, China
Tel：+86-0592-5638526
Fax：+86-0592-5638930
E-mail: export@kasrowpos.com 
http://www.kasrowpos.com